- Effect of Alumina Nanooxide Application on Nitrendipine Manufacturing Process
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E.J. Chae, Y.R. Uhm, B.S. Han, C.K. Rhee, S.E. Park
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J Korean Powder Metall Inst. 2007;14(2):127-131.
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DOI: https://doi.org/10.4150/KPMI.2007.14.2.127
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 Abstract
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- The alumina nano powders synthesized by levitational gas condensation (LGC) method were applied to catalyst in manufacturing process of Hanzsch reaction for Nitrendipine. The L-tartaric acid on the surface is carried out with participation of carbonyl fragments, O-H, C-H bonds which affects stereo selectivity, yield on the reagents positively. From the analysis of the IR-spectroscopy, the carbonyl fragments, O-H, and C-H bond were created by the catalytic reaction. From the analysis of the rR-spectroscopy, the carbonyl fragments, O-H, and C-H bond were created by the catalytic reaction. The newly created bonds made a chiral center on the final product.
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