Abstract

In the present study, silver-doped antibacterial hydroxyapatites were successfully prepared by the sol-gel method. For the starting solution, the molar ratio of Ca(NO_3)_2cdot4H_2O, P(OC_2H_5)_3,;C_2H_5OH,;and;H_O was set to 0.075:0.045:20:0.135; AgNO_3 was added to a ratio of Ag to total cation concentration of 0.5-12 mol%. The prepared sol was dried at 100°C for 48h and heat-treated at 1000°C for 2h to obtain particles in the 200-500nm size range. The product from the synthesis of silver-doped hydroxyapatite was investigated through X-ray diffraction experiments and scanning electron microscopy. The product showed high antibacterial properties, with a disinfection ratio of Staphylococcus aureus (ATCC 6538) and Escherichia coli (ATCC 25922) over 99.9°C as calculated from an antimicrobial effects evaluation by the shake flask method.

• Keywords: Ag-doped hydroxyapatite;anti-microbial properties;sol-gel method;