Ti_50Cu_20Ni_20Al_10 quaternary amorphous alloy was prepared by high-energy ball milling process. A complete amorphization was confirmed for the composition of Ti_50Cu_20Ni_20Al_10 after milling for 30hrs. Differential scanning calorimetry showed a large super-cooled liquid region (DeltaT_x = T_x T_g, T_g and T_x: glass transition and crystallization onset temperatures, respectively) of 80 K. Prepared amorphous powders of Ti_50Cu_20Ni_20Al_10 were consolidated by spark-plasma sintering. Densification behavior and microstructure changes were investigated. Samples sintered at higher temperature of 713 K had a nearly full density. With increasing the sintering temperature, the compressive strength increased to fracture strength of 756 MPa in the case of sintering at 733 K, which showed a 'transparticle' fracture. The samples sintered at above 693 K showed the elongation maximum above 2%.